Jane is Professor of Paediatric Respirology & Experimental Medicine at the National Heart and Lung Institute, Imperial College London, in England and is a National Institute of Health Research Senior Investigator. She is an Honorary Consultant in Paediatric Respiratory Medicine, Royal Brompton Hospital, one of the largest CF clinics in Europe. Her main areas of research interest are cystic fibrosis chronic lung infection and clinical trial design. She directs a Strategic Research Centre focused on Pseudomonas aeruginosa, training future clinical and scientific researchers in CF infection. Jane has been global lead investigator on a large number of international trials of CFTR modulator drugs, including in children and infants and served on Advisory Boards for several companies developing new drugs. She is a founder and Strategy Group member of the UK CF Gene Therapy Consortium. To support paediatric studies, she established the Lung Clearance Core Facility on behalf of the European CF Society, standardizing this more sensitive pulmonary outcome measure. She leads the NIHR CF National Research Strategy Group and is President-elect of the European CF Society.